Explore expert perspectives, scientific advances, and practical strategies to help develop medicines that patients are willing to take.

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Pediatric Investigation Plans: Part 1 – Determining Taste Masking Challenge

Posted by Jeff Worthington on May 11, 2018

Regulations in the EU and US require the development of pediatric dosage forms of every new drug. Pediatric Investigation Plans (for EMA) and Pediatric Study Plans (for FDA) should be submitted early in development, but frequently are filed late and lack specificity. A savvy applicant should take a proactive approach by proposing scientific, stage-gate study plans to fulfill regulatory requirements while mitigating technical and economic risks.

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Palatable Drug Products Defined – It’s More Than Yuck and Yum

Posted by Jeff Worthington on November 18, 2016

By: Jeff Worthington – Senopsys President and Founder Regulations in the United States and European Union are incentivizing (via pediatric exclusivity) and requiring the development of pediatric medicine. These regulations are designed to ensure that every new drug will be evaluated for use in pediatric patients and studied in this population when appropriate. A key

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Definitions of “Flavor” – Implications on Taste Masking

Posted by David Tisi on June 15, 2016
How a Food or Sensory Scientist Defines Flavor

By: David Tisi – Senopsys Technical Director What is Flavor? We can trace the origins of many dosage forms and pharmaceutical technologies back to the food industry – and today we consider it a rich source for approaches, tools and methods that pharmaceutical scientists can adapt to develop palatable drug products. How do we define

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